Vassilios Lougaris Selected Research

Agammaglobulinemia (Hypogammaglobulinemia)

1/2022	Activated phosphoinositide 3-dinase delta syndrome (APDS): An update.
3/2020	Hereditary Deficiency of the Second Component of Complement: Early Diagnosis and 21-Year Follow-Up of a Family.
1/2019	Cerebellar involvement in warts Hypogammaglobulinemia immunodeficiency myelokathexis patients: neuroimaging and clinical findings.
1/2019	A novel monoallelic gain of function mutation in p110δ causing atypical activated phosphoinositide 3-kinase δ syndrome (APDS-1).
1/2019	Comparison of Common Monogenic Defects in a Large Predominantly Antibody Deficiency Cohort.
1/2017	CXCL12 Mediates Aberrant Costimulation of B Lymphocytes in Warts, Hypogammaglobulinemia, Infections, Myelokathexis Immunodeficiency.
1/2016	Cohort of Iranian Patients with Congenital Agammaglobulinemia: Mutation Analysis and Novel Gene Defects.
12/2008	Ig beta deficiency in humans.
9/2008	Autosomal recessive agammaglobulinemia: novel insights from mutations in Ig-beta.
9/2007	Mutations of the Igbeta gene cause agammaglobulinemia in man.

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Vassilios Lougaris Research Topics

Disease

10	Agammaglobulinemia (Hypogammaglobulinemia) 01/2022 - 09/2007
6	Infections 01/2022 - 12/2010
6	Common Variable Immunodeficiency 01/2019 - 09/2005
5	Lymphopenia (Lymphocytopenia) 01/2022 - 01/2016
4	Cytopenia 01/2022 - 01/2017
3	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022 - 08/2015
3	Lung Diseases (Lung Disease) 01/2020 - 03/2016
3	Hypersensitivity (Allergy) 11/2016 - 01/2014
2	Neoplasms (Cancer) 02/2022 - 08/2014
2	Eosinophilia 02/2021 - 08/2015
2	Type 1 Hyper-IgM Immunodeficiency Syndrome 01/2021 - 02/2005
2	Primary Immunodeficiency Diseases 03/2020 - 01/2019
2	WHIM syndrome 01/2019 - 01/2017
2	Warts (Wart) 01/2019 - 01/2017
2	Leukocyte adhesion deficiency type 1 01/2018 - 10/2014
2	Inflammation (Inflammations) 01/2017 - 10/2014
2	Wounds and Injuries (Trauma) 12/2016 - 08/2015
1	Celiac Disease (Celiac Sprue) 02/2022
1	Hereditary Complement Deficiency Diseases 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022
1	Neutropenia 01/2022
1	Evans Syndrome 01/2022
1	Immune System Diseases (Immune Disorders) 01/2022
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2022
1	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 01/2022
1	Staphylococcal Infections 09/2021
1	Splenomegaly 01/2021
1	Bronchiectasis 01/2021
1	COVID-19 11/2020
1	Meningococcal Meningitis 03/2020
1	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 03/2020
1	Reinfection 01/2020
1	severe chronic Neutropenia 01/2019
1	Persistent Infection 01/2019
1	Bacterial Infections (Bacterial Infection) 01/2019
1	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2018
1	Severe combined immunodeficiency due to adenosine deaminase deficiency 01/2018
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 01/2018
1	Chronic Mucocutaneous Candidiasis 08/2017
1	Bone Marrow Failure Disorders 01/2017
1	Milk Hypersensitivity (Milk Allergy) 01/2017
1	Ulcer 12/2016
1	Lymphadenopathy 01/2016
1	Virus Diseases (Viral Diseases) 08/2015
1	Multiple Sclerosis 08/2014
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 08/2014
1	Leukemia 08/2014
1	Job Syndrome (Hyper-IgE Syndrome) 05/2014

Drug/Important Bio-Agent (IBA)

6	Immunoglobulin G (IgG)IBA 01/2022 - 02/2005
6	Immunoglobulins (Immunoglobulin)IBA 01/2022 - 06/2007
6	Immunoglobulin M (IgM)IBA 01/2022 - 02/2005
4	Immunoglobulin A (IgA)IBA 01/2021 - 02/2005
3	Proteins (Proteins, Gene)FDA Link 01/2022 - 09/2007
3	Immunoglobulin E (IgE)IBA 02/2021 - 02/2005
2	LigandsIBA 02/2022 - 12/2010
2	Complement System Proteins (Complement)IBA 01/2022 - 03/2020
2	Pharmaceutical PreparationsIBA 01/2022 - 03/2016
2	Abatacept (Orencia)FDA Link 01/2022 - 01/2022
2	AntigensIBA 09/2021 - 01/2021
2	Agammaglobulinaemia Tyrosine KinaseIBA 01/2019 - 01/2016
2	AntibodiesIBA 01/2019 - 08/2012
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2019 - 01/2016
2	IntegrinsIBA 01/2018 - 10/2014
2	Pre-B Cell ReceptorsIBA 01/2016 - 12/2008
2	B-Cell Activation Factor ReceptorIBA 04/2014 - 09/2005
2	Toll-Like Receptor 9IBA 01/2012 - 12/2010
1	Immune Checkpoint InhibitorsIBA 02/2022
1	CTLA-4 AntigenIBA 02/2022
1	Apoptosis Regulatory ProteinsIBA 02/2022
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022
1	Sirolimus (Rapamycin)FDA Link 01/2022
1	Janus Kinase InhibitorsIBA 01/2022
1	Rituximab (Mabthera)FDA Link 01/2022
1	Inosine Triphosphate (ITP)IBA 01/2022
1	Complement C2 (Complement Component 2)IBA 03/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	CXCR4 Receptors (CXCR4 Receptor)IBA 01/2019
1	Cytidine DeaminaseIBA 01/2019
1	LipopolysaccharidesIBA 01/2019
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2019
1	MacrolidesIBA 01/2019
1	CD40 Ligand (CD40L)IBA 01/2019
1	Adenosine DeaminaseIBA 01/2018
1	STAT1 Transcription FactorIBA 08/2017
1	DNA (Deoxyribonucleic Acid)IBA 08/2017
1	NF-kappa B (NF-kB)IBA 01/2017
1	Chemokine ReceptorsIBA 01/2017
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017
1	Interleukin-10 (Interleukin 10)IBA 01/2017
1	Deoxyribonucleases (DNase)FDA Link 11/2016
1	A-factor (Streptomyces)IBA 08/2014
1	GTP-Binding Proteins (G-Protein)IBA 08/2014
1	Sphingosine-1-Phosphate ReceptorsIBA 08/2014
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 08/2014

Therapy/Procedure

6	Therapeutics 02/2022 - 01/2014
1	Splenectomy 01/2022
1	Conservative Treatment 01/2017
1	Hematopoietic Stem Cell Transplantation 01/2017
1	Aftercare (After-Treatment) 12/2016